崔宏瑋*、王俞均、吳承達:Conformational changes in polysaccharide-based chiral selectors induced by mobile phase composition: effects on enantioselective retention and enantiomer elution order reversal, Journal of Chromatography A, 1742, 465660 (8 February 2025)
成對的手性分子具有相同的物理化學性質,但因其在藥理作用上的差異,手性分離技術的製程開發有著其必要性。多醣體型手性吸附劑在手性分離的應用相當廣泛,但其分子識別機制尚未被充分了解。本研究探討了三種基於直鏈澱粉之吸附劑(Chiralpak ID、IF及IG)的吸附、滯留與手性識別機制。我們於正相模式下...